Title | Prenatal Screening of Down Syndrome |
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Project Leader | |
Name | Rozita Rosli |
Telephone No. | 0389468503 |
rozita@medic.upm.edu.my | |
Faculty | Medicine and Health Science |
IP Information | |
IP Type | Patent |
Filed Date | 25-04-2006 |
Application No. | PI20061883 |
Country Filing | Malaysia |
Applicant | Universiti Putra Malaysia |
Granted Date | |
IP Number | - |
Abstract | |
The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the present invention provides a method for screening Down syndrom fetus using DNA aplification promers and gene specific probe for specifically amplifying and quantifying superoxide dismutase-1 (SOD-1) gene in a pregnant woman. The invention also relates to a diagnostic kit for carrying out the invention method. | |
Technology | PCR |
Inventor | Rozita Rosli, Thilakavathy Karuppiah |
Statement of Novelty | |
Work Start Date | |
Work End Date | |
Classification | |
Commercialised Status | |
Faculty | Medicine and Health Science |